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Understanding FND and Pain: A New Paradigm with Prof Jon Stone

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In this episode, i got the opportunity to interview a person I hugely admire. He is  the person most responsible for putting Functional Neurological Disordeer (FND) on the scientific map. Professor Jon Stone is Professor of Neurology at the University of Edinburgh. Since 1999, he has published over 400 papers, built the world's most widely used patient resource for FND — neurosymptoms.org — and led on international diagnostic criteria.

As you may know, FND is a real, disabling, neurological condition. It affects how the brain processes and generates movement, sensation and — critically for this audience — pain. It is not feigning. It is not malingering. And for many patients, it is treatable. 

keywords

FND, pain, neurology, diagnosis, treatment, neuroimmune, predictive processing, multidisciplinary rehab

key topics

  • FND as a neurological condition affecting movement and sensation
  • The overlap between FND and chronic pain conditions
  • Diagnostic signs like Hoover sign and tremor entrainment
  • The neuroimmune and predictive processing models of FND
  • Multidisciplinary approaches to FND and pain management

Chapters

00:00 Understanding Functional Neurological Disorder (FND)
03:15 The Intersection of FND and Pain
07:44 Defining FND in Modern Medicine
11:28 Clinical Signs and Diagnosis of FND
13:29 FND as a Software Problem
15:52 Prevalence of Chronic Pain in FND Patients
19:08 Mechanisms Behind FND and Pain Overlap
21:10 Reconciling CRPS and FND
23:08 Understanding the Overlap in Pain Conditions
30:26 Predictive Processing and Its Role in FND
35:58 Interdisciplinary Approaches to FND Treatment
43:31 The Role of Pain Physicians in Managing FND
46:15 Resources for Learning About FND

 Resources

neurosymptoms.org - https://neurosymptoms.org
International FND Society - https://fndhope.org
FND in chronic pain clinics: 2023 -  DOI: 10.1111/ene.15892 

CRPS and FND : 2018:  Popkirov S, Hoeritzauer i, Colvin L, doi:10.1136/jnnp-2018 318298 

Pain and FND 2024 review:  Steinruecke M, Mason I, Keen M, et al. J doi:10.1136/jnnp-2023 332810 
Migraine and FND 2025 review:  https://doi.org/10.1093/braincomms/fcaf288 

Disclaimer:
This podcast is for education and general information only and does not replace personalised medical advice. If you are experiencing ongoing pain or distress, please consult your healthcare professional. 

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The Pain Speak podcast is presented by Prof Deepak Ravindran, a NHS Consultant specialising in Pain and Lifestyle Medicine. Dr Ravindran is also the author of the book, 'The Pain Free Mindset'

Get in touch:
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For Clinical Queries and consultations, please go to Berkshire Pain Clinic



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