Next Gen Factor Mimetics: Why Are They Needed?

In this episode of the ISTH Pulse Podcast, host Julia Sandrin Gauer is joined by Dr. Sanjay Ahuja and Dr. Allison Wheeler to discuss the evolving landscape of factor mimetics for hemophilia A. They explore emerging therapies including Mim8, NXT007 and Inno8, the unmet needs that remain despite advances with emicizumab and factor replacement therapy, and what next-generation approaches could mean for the future of hemophilia care. The conversation also covers dosing, efficacy, safety, treatment switching and the patient populations that may benefit most as new therapeutic options continue to emerge.

See a full transcript of this episode here: https://cdn.ymaws.com/www.isth.org/resource/resmgr/2026/transcript_for_podcast_1_sep.pdf