In today's episode, Haylie Pomroy sits down with Dr. Richard Deth, professor of pharmacology at Nova Southeastern University, for a molecular deep dive into neuroinflammation, long COVID, and why some people never fully recover.
Dr. Deth breaks down the NLRP3 inflammasome, the cellular structure behind cytokine storms, and explains why long COVID is fundamentally a failure to turn inflammation off. He covers aluminum adjuvants and their persistence in the body, the overlap between natural COVID exposure and vaccination, and how autism research, which established that low glutathione and cysteine create chronic oxidative stress and neuroinflammation, is now the clearest roadmap we have for understanding post-viral chronic illness.
If you are dealing with long COVID, brain fog, or unexplained neuroinflammation, this conversation on Fast Metabolism Matters gives you the science behind what is actually happening.
Key points:
00:01 Introduction
02:11 How NLRP3 inflammasome drives cytokine storms
04:25 Long COVID as a failure to turn inflammation off
05:48 How autism research prepared Dr. Deth for COVID vaccine concerns
09:47 Inoculation vs. vaccination
11:18 What an adjuvant does and why aluminum is not short-term
14:20 Natural COVID infection vs. vaccination
15:32 mRNA reverse transcription and genomic implications
19:09 Autism research as a roadmap for understanding long COVID
20:38 Autism as a metabolic disorder
23:16 Why the brain is uniquely vulnerable to oxidative stress
25:04 High fructose corn syrup, BPA, pesticides, herbicides
26:44 The NLRP3 inflammasome as a metabolic sensor
32:15 How gluten and casein block cysteine absorption
34:57 Nutritional deficiencies cannot be solved by pharmaceuticals alone
36:36 How low glutathione increases the risk of adverse drug effects
If your body feels like it's running on empty, overburdened, or just not responding the way it used to, Haylie's latest book, Toxic Overload, tells you exactly what to do. Download your free digital copy today and start understanding what your body is trying to tell you.
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Dr. Richard Deth is a molecular neuroscientist at Nova Southeastern University, where he has worked since 2014 after 38 years at Northeastern University. His research focuses on brain disorders like autism, exploring neurodevelopment, aging, attention, and learning. He studies neurons' metabolic features, particularly the antioxidant glutathione (GSH), its role in methylation, and epigenetic regulation. Dr. Deth investigates how casein and gluten-derived opioid peptides impair cysteine absorption, affecting antioxidant levels and epigenetics. His current work examines oxidative stress, inflammation, and the anti-inflammatory potential of cobinamide, a vitamin B12 precursor.
LinkedIn: https://www.linkedin.com/in/richard-deth-2383175/
Haylie Pomroy, Founder and CEO of The Haylie Pomroy Group, is a leading health strategist specializing in metabolism, weight loss, and integrative wellness. With over 25 years of experience, she has worked with top medical institutions and high-profile clients, developing targeted programs and supplements rooted in the "Food is Medicine" philosophy. Inspired by her own autoimmune journey, she combines expertise in nutrition, biochemistry, and patient advocacy to help others reclaim their health. She is a New York Times bestselling author of The Fast Metabolism Diet.
Learn more about Haylie Pomroy's approach to wellness through her website: https://hayliepomroy.com
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