SART Fertility Experts - Genetic Risk, Guidelines, and Gray Areas in Donor Selection

In this episode, we speak with Katherine Hornberger, MS, CGC who is genetic counselor at Seattle Sperm Bank with over 10 years of experience in the assisted reproductive technology space. We unpack how donor genetic screening actually works—from intake and family history review to expanded carrier screening and final eligibility decisions. We explore how multifactorial conditions like autism, mental health disorders are evaluated, how ASRM guidelines shape practice, and where ethical gray areas emerge. Our guest also addresses common misconceptions about genetic risk, the limitations of family history, and what recipients should realistically consider when choosing a donor. This conversation offers a rare inside look at the science, safeguards, and judgment calls behind donor selection.

Find the #StartwithSART Fertility Experts series wherever you get your podcasts. Looking for advice on building a family? Ask the experts and #StartwithSART.

For more information about the Society for Assisted Reproductive Technology, visit our website at https://www.sart.org

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