For over six decades, conventional medical advice has treated weight management as a simple accounting problem: calories in versus calories out. Yet traditional diet and exercise programs consistently fail to stop rising obesity rates. Why? Because that simple equation ignores millions of years of human evolution and the complex biological mechanisms the body uses to actively defend its weight.
In this episode of the Nature and Science Podcast, host Donald Murphy sits down with renowned pediatric surgeon and researcher Dr. Evan Nadler to challenge how we define, diagnose, and treat obesity.
Together, they explore: • Why calories in vs. calories out fails to explain cellular weight defense • The role of epigenetics and the in-utero environment in shaping long-term metabolic health • How fat cells function as an active biological organ • Why obesity must be understood as a biological disease rather than a lifestyle or willpower failure • The systemic barriers facing families today and the critical need for expanded access to pediatric care
Whether you are a healthcare professional, parent, or simply interested in the biological frontiers of human health, this conversation offers a fresh, evidence-based paradigm shift on metabolic science.
-------------------------------------------------- RESOURCES & LINKS MENTIONED: • Learn more about the Nature and Science Podcast: https://natureandsciencepodcast.com • Submit a guest pitch or proposal: https://natureandsciencepodcast.com/guest-proposals
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