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Tirofiban resulted in greater 90-day excellent neurological outcomes vs. placebo in patients with no medium or large vessel occlusion (LVO) who were not improving with with tenecteplase (TNK), NNT = 9.
Dual antiplatelet therapy (DAPT) with ticagrelor plus aspirin vs. placebo in patients with stroke treated with thrombolysis resulted in better 90-day excellent neurological outcome, NNT = 15, without a significant increase in symptomatic intracranial hemorrhage (sICH).
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