When Antipsychotics Aren’t the Answer: The Medical Illness That Can Look Like Psychosis

Hallucinations, paranoia, agitation, and bizarre behavior can reasonably lead clinicians toward antipsychotic treatment, but what happens when the underlying illness isn’t primarily psychiatric? Anti-NMDA receptor encephalitis can initially resemble a severe psychiatric disorder before neurological symptoms emerge. This episode examines the diagnostic clues that can change the entire treatment strategy.