Episode 7: Key biomaterial parameters found for optimal organoid morphogenesis

In this podcast episode, MRS Bulletin’s Laura Leay reports on the quantified relationship between rheology of a granular biomaterial and tissue self-organization, a study conducted by research groups at the University of California, the Chan Zuckerberg Biohub in San Francisco, Stanford University, and Cedars-Sinai in Los Angeles. The collaborators developed a 3D-bioprinter with a piezoelectric print head to control mechanical forces and a composite extracellular matrix for the biomaterial. One aim of the research was to demonstrate a print medium that could be used to produce a wide variety of biological structures. This work was published in a recent issue of Nature Materials.