What is it?
Colorectal cancer
3rd most diagnosed cancer in US (men & women)
S/S = blood in stool, GI irritation, irregular stools, chronic diarrhea, sudden weight loss
Diagnostic = colonoscopy – polyps, inflammation, ulcers, abnormal growths
ACS testing guidelinesAsymptomatic, negative family history, no polyps – every 10 years
Low-risk polyps – 5 years
High-risk polyps
What causes it?
CauseAge (90% of cases for people > 50 y/o)
Family history
Race – African Americans (new Dx 20% higher in Blacks, and death rates 40% higher)
Ethnicity – Ashkenazi Jews
Ulcerative colitis, Crohn’s disease
Low whole grain diets
Genetic predisposition
Smoking, alcohol use, lack of exercise, diabetes
How is it treated?
Stage O, I -- Sx
Stage II – Sx + Adj Chemo
Stage III – Sx + Adj Chemo
Stage IV – Sx + ChemoChemo + Targeted Tx
Gene types – + immunotherapy
Radiation
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