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The New Science of Brain Aging: What 200,000 scans reveal | Paul Thompson, PhD

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How well is your brain aging? Your birthday tells you one thing, but your brain may tell a different story.

Today, I’m talking with neuroscientist Paul Thompson, PhD, whose work with the global ENIGMA Consortium is revealing how brain health connects to what’s happening throughout your body. We get into what brain scans can tell us and why those findings matter to you.

We discuss:

What your “brain age” means and how it can differ from your actual age

Why your metabolic health deserves attention when you’re struggling with mood or memory

How sleep and nutrition support your brain’s ability to function and recover

What having an Alzheimer’s risk gene does, and doesn’t, tell you about your future

How brain scans, blood tests, and AI could help identify the right treatment for you

It’s so exciting to see researchers like Paul looking across thousands of brain scans and uncovering connections between the health of the body and the brain. For me, it opens up a bigger conversation about how we care for ourselves and how our everyday habits can help protect our memory and support our mood as we age.

View Show Notes From This Episode

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0:00 Paleo Valley Superfood Bars

2:50 Enigma and Brain Mapping

10:30 Psychiatry Meets Brain Biology

18:35 The Brain-Body Connection

24:30 Mapping Mental Health Patterns

31:30 Brain Age and Biomarkers

36:59 Sleep, Nutrition, and Recovery

47:38 A Case of Brain Repair

52:50 Genes, Risk, and Protection

59:15 Brain Charts and Diagnostics

1:12:26 AI for Alzheimer’s Disease

1:20:06 Imaging and Prevention

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