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What if your ovaries influence your metabolism, inflammation, sleep, and long-term health, not just your ability to have children? In this episode of hol+, Dr. Taz MD speaks with reproductive biologist and Celmatix founder Dr. Piraye Beim about the emerging field of ovarian health.
Dr. Beim explains why the ovary should be understood as a metabolic, immune, and endocrine organ that communicates with tissues throughout the body. She reveals what may happen when ovarian function begins declining, why perimenopause can feel so sudden, and how those changes may influence weight, insulin signaling, inflammation, and healthy aging.
The conversation also explores AMH and ovarian reserve, the overlooked 300-day process behind egg development, and the experimental treatments scientists are developing to regulate ovarian function and potentially extend ovarian health.
Dr. Beim also shares practical ways women can support the ovarian function they have today, including reducing smoking and toxin exposure, managing inflammation, protecting sleep, getting appropriate morning light, exercising, and supporting metabolic health.
In this episode, you’ll learn:
• Why ovarian health affects much more than fertility
• How ovarian function interacts with metabolism and inflammation
• Why weight management can become harder during perimenopause
• What high or low AMH may reveal about ovarian function
• How PCOS and endometriosis can affect ovarian health
• Why sleep and light exposure matter for hormone signaling
• Whether lifestyle changes may influence ovarian aging
• What the future of fertility and menopause treatment could look like
The AMH-mimicking treatment discussed in this conversation remains experimental and is still being developed.
Dr. Taz and Dr. Beim also discuss PCOS, endometriosis, diminished ovarian reserve, fertility treatments, and the overlooked 300-day process behind the development of an egg. Dr. Beim shares how Celmatix is developing an experimental therapy designed to mimic AMH and potentially regulate how quickly ovarian follicles are used over a woman’s lifetime.
If you have struggled with fertility, PCOS, painful periods, perimenopause, menopause, unexplained weight changes, or low AMH, this conversation offers a new way to understand the connection between your ovaries and your overall health.
The AMH-mimicking treatment discussed in this episode is still under development and has not been proven or approved to extend ovarian function in humans.
About Dr. Piraye Beim:
Dr. Piraye Beim is a reproductive biologist, women’s health innovator, and founder and CEO of Celmatix. For more than 20 years, she has worked to advance the scientific understanding of female biology, fertility, ovarian aging, and reproductive health. Through Celmatix, she is helping pioneer the field of ovarian health and develop new therapies intended to improve fertility care, regulate ovarian function, and support women’s health across the lifespan. She also shares ovarian-health education and her personal journey through Boss Ovary.
Connect with Dr. Piraye Beim:
https://www.celmatix.com/
https://www.instagram.com/bossovary/
https://www.linkedin.com/company/celmatix/
About Dr. Taz:
Dr. Tasneem Bhatia (Dr. Taz) is a triple board-certified integrative medicine physician, bestselling author, and founder of hol+, a multi-location integrative medicine practice.
Learn more: https://doctortaz.com/about
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Produced by https://ClipGrowth.com (Producer: Pat Gostek)
