Partial Thromboplastin Time (PTT) Lab Values

Normal 25 - 35 seconds

Indications

• Detection of coagulation disorders
• Evaluate response to Heparin (PT for Coumadin)
• Preoperative assessment

Description

Partial Thromboplastin Time (PTT)evaluates the function of factors I, II, V, VIII, IX, X, XI, and XII. PTT represents the amount of time required for a fibrin clot to form. Monitors therapeutic ranges for people taking Heparin.

What would cause increased levels?

• Disseminated Intravascular Coagulation (DIC)
• Clotting Factor Deficiencies:
  • Hypofibrinogenemia
  • Von Willebrand Disease
  • Hemophilia
• Liver disease:
  • Cirrhosis
• Vitamin K deficiency
• Polycythemia
• Dialysis

What would cause decreased levels?

• N/A