The Substance is a 2024 body horror film written and directed by French filmmaker Coralie Farageat, starring Demi Moore, Margaret Qualley, and Dennis Quaid. The film follows a recently displaced celebrity who decides to take a secret drug that temporarily creates a younger version of herself with unexpected side effects. All that and a discussion of films that make you squirm. The one and only Katya Zamolodchikova joins us.
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