Dr Chris Smith and the Naked Scientist team delve into the science of computer simulation and ask whether we could be living in the Matrix. Could our reality have been created by a computer? Plus, we meet the people using computer simulation to improve our lives, from predicting the weather to understanding more about the human heart. Also, cancer drugs disguised as fat cells, how cigarette butts are harming our plants, and why canned laughter makes jokes funnier.

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