New research from Northwestern Medicine reveals women are hit harder by long COVID’s neurological toll—brain fog, numbness, and crushing fatigue are disproportionately affecting them, slashing daily function and quality of life. Women also report more autonomic issues like shortness of breath and chest pain. Dr. Igor Koralnik calls it a “silent epidemic,” warning that lingering symptoms are still widespread and often overlooked. Scientists suspect women’s stronger immune response—while protective against acute infection—may make them more vulnerable to long-term autoimmune effects. For 28-year-old Grace Huffman-Gottschling, the toll is real: brain fog and fatigue have turned everyday tasks into battles, leaving her drained beyond work. This gender-specific impact demands urgent, targeted solutions.

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