Christian McCaffrey’s health is the biggest question mark for the 49ers’ offense this season—his durability is a ticking clock, and his absence would cripple their attack. At 30, his body can’t keep up with the workload that made him a game-changer last year, and even with careful management, he’s likely to miss games. Without him, the team’s explosive backfield threat vanishes, leaving Jordan James and rookie Kaelon Black to fill a void they can’t possibly fill. McCaffrey isn’t just a runner—he’s the engine that forces defenses to bend, opening lanes for everyone else. His health isn’t just important; it’s the key to unlocking the 49ers’ ceiling.
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