In this episode of Fast Physiology on the Critical Oxygen Podcast, Dave Schell and I discuss fatigue. We explore the physiological mechanisms, the role of ATP in muscle contraction, and how specific training can enhance fatigue resistance. We discuss the protective nature of fatigue (i.e. why we fatigue), the importance of understanding metabolic acidosis, and the need for tailored training to prepare for endurance events. The conversation emphasizes the multifactorial aspects of fatigue and the significance of maintaining ATP levels during exercise.

TAKEAWAYS

- Fatigue is a protective mechanism to prevent catastrophic muscle damage.

- Mitochondria help buffer hydrogen ions during exercise.

- Factors like heat, and metabolic acidosis contribute to fatigue through different mechanisms.

If you have a question or topic you want us to address, leave a comment!

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CHAPTERS

00:00 Understanding Fatigue: A Protective Mechanism

07:00 Physiological Mechanisms Behind Fatigue

13:07 The Role of ATP and Muscle Contraction

21:05 Training for Fatigue Resistance

25:01 Key Takeaways and Conclusion

KEYWORDS

fatigue, exercise physiology, ATP, muscle contraction, endurance training, metabolic acidosis, performance, fatigue resistance, physiological mechanisms, training adaptation

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