People with bipolar disorder are four to six times more likely to die prematurely compared to those without a psychiatric disorder. (In comparison, smokers are two to three times more likely to have a shortened lifespan.) There are several contributing factors, including things like metabolic dysfunction, as well consequences of lifestyle choices influenced by disease burden Science needs to urgently investigate these extremely poor outcomes in search of more effective interventions that will enhance quality of life for people with bipolar disorder. Emerging evidence and clinical experience indicate that ketogenic and metabolic therapies may have a central role in addressing this concerning trend.
Dr. Bret Scher interviews Dr. Melvin McInnis, Professor of Bipolar Disorder and Depression at University of Michigan, on these pressing topics. Dr. McInnis is working on a pilot trial that will look at a “ketogenic mimicking diet,” augmenting a low carb diet with exogenous ketones in bipolar disorder. Could this address unwanted metabolic dysfunction in this population? We applaud Dr. McInnins and his team for asking the question.
Experts in this episode:
Melvin McInnis, M.D., FRCPsych
https://medicine.umich.edu/dept/psychiatry/melvin-mcinnis-md
https://medicine.umich.edu/dept/prechter-program/melvin-g-mcinnis-md-frcpsych
Study
The Heinz C. Prechter Longitudinal Study of Bipolar Disorder
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837550/
If you or a loved one are looking to begin ketogenic therapy for a psychiatric condition, visit this page for resources:
https://www.metabolicmind.org/families-and-peers
Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.
Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/
About us:
Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.
Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.
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