In a study evaluating dose-response to a moderate and high Anadrol dosage, muscle and strength gains from 50 mg per day and 100 mg per day were compared.
By now you've probably heard me outline the "less is more" concept when it comes to steroid use.
On one side of the spectrum, the clinical data does show that the more steroids you use, the more muscle you will gain over the span of a cycle.
However, the same studies also reveal a dose-dependent decline in muscle growth response relative to increased drug load.
Basically, more works better, but there are diminishing returns the higher your dosages go, and how much muscle you net over the span of your life bodybuilding will likely differ based on how aggressively you approach your mass building phases.
https://youtu.be/JmICCDzhKRo
50 mg Vs. 100 mg Anadrol Study Results In the following study, we can see changes in body weight, lean body mass (what we mainly care about), and fat loss in response to a moderate and high Anadrol dosage (50 mg vs. 100 mg) [R].
The placebo group didn't gain any lean body mass, nor did they lose any body fat.
The 50 mg Anadrol treated group gained 3.3 kilograms of lean body mass and lost 2.6 kg of fat.
The 100 mg Anadrol treated group gained 4.2 kilograms of lean body mass and lost 2.5 kg of fat.
Looking at lean body mass, we can see that when comparing the two dosage groups, the 100 mg group only gained 0.9 kg lean body mass more than the 50 mg group.
This is after three-month exposure to twice the amount of drug.
If we compare biomarkers between the two groups, we can see that the effect 100 mg of Anadrol had on ALT and AST levels was far more deleterious than the 50 mg group.
Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) are commonly used biomarkers for assessing liver damage.
Placebo 50 mg/day 100 mg/day PValue ALT, U/l 0 ± 2 21 ± 15 72 ± 67 0.001 AST, U/l 1 ± 2 14 ± 6 38 ± 29
