Patrick Gleeson began experimenting with electronic music in the mid-'60s at the San Francisco Tape Music Center using a Buchla synthesizer and other devices. In 1968, upon hearing Wendy Carlos' “Switched-On Bach”, he bought a Moog synthesizer and opened the Different Fur recording studio in San Francisco.

He worked with Herbie Hancock in the early 1970s, touring with Hancock – thus pioneering the use of synthesizers outside the studio – and appearing on the albums "Crossings" and "Sextant". 

Hancock's “Sextant” and “Headhunters” were both recorded in part at Different Fur studios. Gleeson has worked with many other Jazz musicians including Freddie Hubbard, Charles Earland, Eddie Henderson, Joe Henderson, and Lenny White.

Gleeson recorded a number of solo albums, starting with “Beyond the Sun” - An Electronic Portrait of Holst's "The Planets" in 1976. The album was nominated for a "Best Engineered Recording: Classical" Grammy in 1976. “Beyond the Sun” was followed in 1977 by a more commercial album, titled “Star Wars”.

Pat worked as an engineer on the 1978 Devo album “Q: Are We Not Men? A: We Are Devo!”, part of which was recorded at Different Fur. Gleeson has been involved in the scoring of a number of film soundtracks, including “The Plague Dogs”, “Apocalypse Now”, and “Crossroads and The Bedroom Window”. He has scored nine television series, including “Knots Landing”.

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