Engineering yeast to produce medicines, and the mechanism of anaesthetic action.
In this episode:
00:44 Making medicine with yeast
The tropane alkaloids are an important class of medicine, but they are produced agriculturally leaving them vulnerable to extreme weather and world events. Now, researchers have engineered yeast to produce these important molecules. Research Article: Srinivasan and Smolke
19:07 The molecular mechanisms of general anaesthetics
Despite over a century of use, there’s a lot we don’t know about how anaesthetics function. This week, researchers have identified how some of them they bind to a specific neuronal receptor. Research Article: Kim et al.
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