Airdate January 24, 2021: President Biden swiftly took action to move away from many of the policies of the last 4 years. What is the reaction from U.S. allies and competitors? Fareed gets perspectives from the UK, China, Germany and Mexico. Then, as Covid cases worldwide approach 100-million, new variants have cropped up, and vaccine rollouts are underway. Is herd immunity on the horizon? CNN's chief medical correspondent Sanjay Gupta answers pressing questions about COVID-19 and tells Fareed about his latest book "Keep Sharp: Build a Better Brain at Any Age."

GUESTS: David Miliband, Keyu Jin, Wolfgang Ischinger, Jorge Castañeda, Sanjay Gupta

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