Dr. Gary S. Sachs (Harvard Medical School) joins us for the for the March episode of AJP Audio, discussing the results from a phase 3 study looking at the use of atypical antipsychotic cariprazine as an adjunctive treatment for major depression in conjunction with antidepressants.  Afterwards, we’ll be joined once again by AJP Editor-in-Chief Dr. Ned Kalin to discuss the rest of the March issue.

Transcript

  • Sachs interview [00:47]
  • Why is treating major depressive disorder in patients proven to be such a challenge for clinicians? [01:54]
  • Why cariprazine in conjunction with antidepressants? [02:37]
  • Atypical antipsychotics and antidepressants [03:22]
  • Atypical antipsychotics and side effects [05:23]
  • Limitations [07:09]
  • Clinical implications for the treatment of major depressive disorder [08:29]
  • What’s next for your research? [09:15]
  • Kalin interview [10:09]
  • Sachs et al. [10:25]
  • Hasseris et al. [12:35]
  • Visontay et al. [15:15]
  • Dunlop et al. [17:10]
  • Elbau et al. [19:56]

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