Mitochondria are the powerhouses of the cell which function to make ATP and energy. Their role in chronic disease is widely studied and often overlooked. Symptoms and root causes of mitochondrial dysfunction can be difficult to pinpoint in your patients. When it comes to relating this to brain fatigue or thyroid dysfunction, Dr. Datis Kharrazian is an expert. He has written several books and lectured extensively on these topics.

In this episode, Dr. Kharrazian outlines his approach to chronic disease using the lost art of the physical exam, laboratory assessments, and a review of current literature. Learn how he uses subtle clues to uncover root causes and what he does to improve patient outcomes.

 “One of your best windows to assess mitochondrial compromise is to look at the brain.” – Dr. Datis Kharrazian

Today on The Lab Report:

2:40 Meet Dr. Datis Kharrazian

10:10 Mitochondrial dysfunction and how it affects the brain

13:00 Symptoms, causes, and treatment of brain fatigue

19:00 The functional neurological exam

21:00 Stimulating neurologic mitochondrial biogenesis

22:50 Working up brain fatigue with functional labs and physical exam

28:05 Functional medicine approach to autoimmune thyroid disease

31:32 Intestinal permeability, gluten, and lectins in autoimmunity

39:00 Using stool testing and food antibody testing to assess immune tolerance

43:40 Kharrazian explains his extensive new patient work up

48:35 The Kharrazian Institute

53:25 The Fireball

Additional Resources:

Kharrazian Resource Center

Kharrazian Institute

Why Isn't My Brain Working?

Why Do I Still Have Thyroid Symptoms When My Lab Tests Are Normal?

Immunological Reactivity Using Monoclonal and Polyclonal Antibodies of Autoimmune Thyroid Target Sites with Dietary Proteins

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